Print Email Facebook Twitter Docosahexaenoic acid production by the marine algae Crypthecodinium cohnii Title Docosahexaenoic acid production by the marine algae Crypthecodinium cohnii Author De Swaaf, M.E. Contributor Pronk, J.T. (promotor) Faculty Applied Sciences Date 2003-04-07 Abstract This thesis focuses on the production of docosahexaenoic acid (DHA; 22:6), an w-3 polyunsaturated fatty acid with applications in foods and pharmaceuticals, by Crypthecodinium cohnii. This chloroplastless heterotrophic marine microalga has been studied since the end of the nineteenth century and has been identified as a good producer of DHA. C. cohnii can accumulate lipid to over 20% of its biomass dry weight, with a high content of DHA (over 30% of the total lipid). Other polyunsaturated fatty acids represent less than 1% of the C. cohnii-derived oil. The aim of the research described in this thesis was to identify relevant process parameters for the large-scale production of docosahexaenoic acid (DHA) with C. cohnii. Several cultivation protocols for C. cohnii were developed, analysed and optimised with respect to the production of biomass, lipid and DHA and solutions were sought for newly identified bottlenecks for industrial DHA production. Subject crypthecodinium cohniidocosahexaenoic acidmarine algae To reference this document use: http://resolver.tudelft.nl/uuid:dbe725de-614f-41be-adba-85e4ee7ae949 Publisher Delft University Press ISBN 90-407-2400-8 Part of collection Institutional Repository Document type doctoral thesis Rights (c) 2003 M.E. de Swaaf Files PDF as_swaaf_20030407.pdf 973.01 KB Close viewer /islandora/object/uuid:dbe725de-614f-41be-adba-85e4ee7ae949/datastream/OBJ/view