Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans123
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KEY WORDS
Polyphenol
coffee
tea
chlorogenic acid
quercetin-3-rutinoside
homocysteine
cardiovascular disease
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- 1
From the Division of Human Nutrition and Epidemiology, Wageningen University, Wageningen, Netherlands; the State Institute for Quality Control of Agricultural Products (RIKILT), Wageningen, Netherlands; and the Wageningen Centre for Food Sciences, Wageningen, Netherlands.
- 2
Supported by the Foundation for Nutrition and Health Research, Netherlands. Black tea solids were kindly provided by Unilever Research Vlaardingen, Vlaardingen, Netherlands.
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Reprints not available. Address correspondence to MR Olthof, Division of Human Nutrition and Epidemiology, Wageningen University, PO Box 8129, 6700 EV Wageningen, Netherlands. E-mail: [email protected].
Copyright © 2001 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.